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David A Wink Selected Research

oxyhyponitrite

12/2005Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo.
1/2005Mechanism of aerobic decomposition of Angeli's salt (sodium trioxodinitrate) at physiological pH.
5/2002Further evidence for distinct reactive intermediates from nitroxyl and peroxynitrite: effects of buffer composition on the chemistry of Angeli's salt and synthetic peroxynitrite.

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David A Wink Research Topics

Disease

52Neoplasms (Cancer)
11/2021 - 01/2003
20Breast Neoplasms (Breast Cancer)
01/2020 - 09/2002
12Inflammation (Inflammations)
01/2019 - 01/2003
8Neoplasm Metastasis (Metastasis)
11/2021 - 07/2006
8Heart Failure
01/2016 - 04/2003
7Ischemia
02/2022 - 01/2003
6Hypoxia (Hypoxemia)
11/2021 - 09/2005
5Carcinogenesis
01/2021 - 09/2008
5Carcinoma (Carcinomatosis)
01/2018 - 08/2002
3Reperfusion Injury
02/2022 - 02/2007
3Hepatocellular Carcinoma (Hepatoma)
12/2020 - 03/2009
3Triple Negative Breast Neoplasms
01/2019 - 01/2016
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2018 - 05/2010
3Adenocarcinoma
06/2015 - 03/2009
3Alzheimer Disease (Alzheimer's Disease)
12/2012 - 12/2008
3Cardiovascular Diseases (Cardiovascular Disease)
10/2008 - 05/2002
2Infarction (Infarctions)
02/2022 - 01/2003
2Prostatic Neoplasms (Prostate Cancer)
01/2021 - 01/2020
2Disease Progression
01/2017 - 12/2014
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
07/2015 - 03/2008
2Lung Neoplasms (Lung Cancer)
02/2012 - 07/2010
2Melanoma (Melanoma, Malignant)
09/2008 - 08/2008
2Wounds and Injuries (Trauma)
10/2007 - 01/2005
1Endometrial Neoplasms (Endometrial Cancer)
10/2019
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2019
1Experimental Melanoma
01/2018
1Liver Neoplasms (Liver Cancer)
01/2017

Drug/Important Bio-Agent (IBA)

34Nitric Oxide (Nitrogen Monoxide)FDA Link
02/2022 - 01/2003
12Estrogen ReceptorsIBA
12/2017 - 11/2010
12Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2017 - 09/2008
11nitroxylIBA
02/2022 - 05/2002
9Nitric Oxide Synthase (NO Synthase)IBA
10/2019 - 01/2003
9Proteins (Proteins, Gene)FDA Link
01/2017 - 01/2003
6Nitrogen OxidesIBA
10/2019 - 05/2002
5EnzymesIBA
01/2019 - 07/2004
5Cyclooxygenase 2 (Cyclooxygenase-2)IBA
12/2017 - 02/2007
5Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
12/2017 - 02/2012
4Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
03/2018 - 03/2009
4Matrix Metalloproteinases (MMPs)IBA
01/2017 - 10/2007
4ProdrugsIBA
06/2015 - 11/2010
4Reactive Oxygen Species (Oxygen Radicals)IBA
02/2012 - 05/2002
3Free RadicalsIBA
11/2021 - 01/2003
3AntioxidantsIBA
03/2018 - 07/2004
3MorpholinosIBA
07/2015 - 03/2007
3Interleukin-8 (Interleukin 8)IBA
04/2014 - 11/2010
3Cadherins (E-Cadherin)IBA
09/2012 - 05/2010
3oxyhyponitriteIBA
12/2005 - 05/2002
2Oxygen (Dioxygen)IBA
01/2021 - 09/2002
2Protein Isoforms (Isoforms)IBA
12/2020 - 10/2019
2Pharmaceutical PreparationsIBA
01/2020 - 10/2009
2Nitric Oxide DonorsIBA
10/2019 - 01/2005
2RNA (Ribonucleic Acid)IBA
10/2019 - 09/2012
2NG-Nitroarginine Methyl Ester (L-NAME)IBA
01/2019 - 07/2015
2Indomethacin (Indometacin)FDA LinkGeneric
12/2017 - 02/2012
2ErbB Receptors (EGF Receptor)IBA
01/2017 - 07/2010
2Mitogen-Activated Protein KinasesIBA
01/2017 - 12/2010
2ElementsIBA
01/2017 - 09/2012
2Interleukin-2 (IL2)IBA
07/2015 - 10/2010
2diazeniumdiolateIBA
06/2015 - 10/2013
21,1-diethyl-2-hydroxy-2-nitrosohydrazineIBA
12/2014 - 01/2003
2Amyloid beta-PeptidesIBA
12/2012 - 12/2008
2Matrix Metalloproteinase 9 (Gelatinase B)IBA
12/2012 - 05/2012
2Peptides (Polypeptides)IBA
12/2012 - 07/2010
2Estrogens (Estrogen)FDA Link
05/2012 - 11/2010
2Transcription Factors (Transcription Factor)IBA
05/2012 - 12/2006
2Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
11/2011 - 09/2005
2CannabidiolIBA
05/2011 - 12/2010
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2011 - 12/2010
2Messenger RNA (mRNA)IBA
05/2011 - 08/2009
2Caspase 9IBA
11/2010 - 02/2007
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2010 - 08/2008
2S-sulindacIBA
05/2010 - 03/2009
22- ((2,6- dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl esterIBA
05/2010 - 03/2009
2DNA (Deoxyribonucleic Acid)IBA
03/2009 - 10/2008
2Thrombospondin 1IBA
09/2008 - 08/2008
2BuffersIBA
01/2003 - 09/2002
1KATP ChannelsIBA
02/2022
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
02/2022
1Tetrazolium SaltsIBA
02/2022
1cyclamIBA
01/2020
1Glutamine (L-Glutamine)FDA Link
01/2020
1Oxidoreductases (Dehydrogenase)IBA
01/2020
1Pyruvic Acid (Pyruvate)IBA
01/2020
11- hydroxy- 2- oxo- 3,3- bis(2- aminoethyl)- 1- triazeneIBA
10/2019
1Cyclin-Dependent Kinases (cdk Proteins)IBA
10/2019
1Indicators and Reagents (Reagents)IBA
01/2019
1Dinoprostone (PGE2)FDA Link
01/2019
1Retinaldehyde (Retinal)IBA
03/2018
1itaconic acidIBA
01/2018
1Aconitic Acid (Aconitate)IBA
01/2018
1Fatty Acids (Saturated Fatty Acids)IBA
01/2018
1Small Interfering RNA (siRNA)IBA
01/2018
1Guanidine (Guanidine Nitrate)FDA Link
12/2017
1Biomarkers (Surrogate Marker)IBA
10/2017
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2017

Therapy/Procedure

17Therapeutics
11/2021 - 02/2007
4Immunotherapy
01/2020 - 10/2010
4Radiotherapy
01/2020 - 07/2004
2Drug Therapy (Chemotherapy)
03/2013 - 06/2009
1Photochemotherapy (Photodynamic Therapy)
01/2021